Víbora Cornuda Africana

Bites are assumed to be rare and no epidemiological data is available. Little information is available regarding the toxicity and amount of venom produced. Spawls and Branch (1995) reported an average yield of 85 mg of wet venom, while Christensen (1971) offered an LD50 value of 1.2 mg/kg IV. Other research has found the LD50 to be between 0.15 and 0.22 mg/kg Based on this LD50 value, Spawls and Branch (1995) estimated about 300 mg of this venom would be required to kill an adult. They regarded this venom as one of the weakest of the genus, although the tests are conducted solely on mice, which might have a different reaction from humans to the venom. On the other hand, an older report by the U.S. Navy (1965, 1991) suggested it is highly toxic and a number of deaths have occurred as a result. According to Broadley and Cock (1975), envenomation symptoms in humans include swelling, severe pain, nausea, vomiting and shock. Blisters and necrotic ulcers may form around the bite site. The National Antivenom and Vaccine Production Centre in Riyadh, Saudi Arabia, produces a polyvalent antivenin that includes a paraspecific antibody that protects against bites from this species. According to the U.S. Navy (1965, 1991), polyvalent antivenins produced by SAIMR and the Pasteur Institute are said to be effective, while Mallow et al. …